Common Name: 1,2-Dichloropropane
CAS Number: 78-87-5
DOT Number: UN 1279
Date: June 30, 1986
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HAZARD SUMMARY
* 1,2-Dichloropropane can affect you when breathed in and by
passing through skin.
* The vapor can irritate the nose, throat, eyes and air
passages.
* Repeated or prolonged skin contact can cause rash.
* High or repeated exposure can damage the liver, kidneys and
brain. Early symptoms include headaches, nausea, personality
changes.
* High exposure can irritate the lungs. It can also make you
lightheaded, dizzy and cause you to pass out.
* 1,2-Dichloropropane is a FLAMMABLE LIQUID and a FIRE HAZARD.
IDENTIFICATION
1,2-Dichloropropane is a colorless liquid with a chloroform like
odor. It is used as a solvent, degreaser, in dry cleaning fluids
and as an insecticide.
REASON FOR CITATION
* 1,2-Dichloropropane is on the Hazardous Substance List because
it is regulated by OSHA and cited by ACGIH, DOT and NFPA.
* This chemical is on the Special Health Hazard Substance List
because it is FLAMMABLE.
* Definitions are attached.
HOW TO DETERMINE IF YOU ARE BEING EXPOSED
* Exposure to hazardous substances should be routinely
evaluated. This may include collecting personal and area air
samples. You can obtain copies of sampling results from your
employer. You have a legal right to this information under
OSHA 1910.20.
* If you think you are experiencing any work related health
problems, see a doctor trained to recognize occupational
diseases. Take this Fact Sheet with you.
* ODOR THRESHOLD = 0.25 ppm.
* The odor threshold only serves as a warning of exposure. Not
smelling it does not mean you are not being exposed.
WORKPLACE EXPOSURE LIMITS
OSHA: The legal airborne permissible exposure limit (PEL) is
75 ppm averaged over an 8 hour workshift.
ACGIH: The recommended airborne exposure limit is 75 ppm
averaged over an 8 hour workshift and 110 ppm as a STEL
(short term exposure limit).
* The above exposure limits are for air levels only. When skin
contact also occurs, you may be overexposed, even though air
levels are less than the limits listed above.
WAYS OF REDUCING EXPOSURE
* Where possible, enclose operations and use local exhaust
ventilation at the site of chemical release. If local exhaust
ventilation or enclosure is not used, respirators should be
worn.
* Wear protective work clothing.
* Wash thoroughly immediately after exposure to 1,2-
Dichloropropane and at the end of the workshift.
* Post hazard and warning information in the work area. In
addition, as part of an ongoing education and training effort,
communicate all information on the health and safety hazards
of 1,2-Dichloropropane to potentially exposed workers.
This Fact Sheet is a summary source of information of all potential
and most severe health hazards that may result from exposure.
Duration of exposure, concentration of the substance and other
factors will affect your susceptibility to any of the potential
effects described below.
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HEALTH HAZARD INFORMATION
Acute Health Effects
The following acute (short term) health effects may occur
immediately or shortly after exposure to 1,2-Dichloropropane:
* The vapor can irritate the eyes, nose, throat and air
passages.
* Eye contact causes strong irritation.
* High exposure can damage the liver, kidneys and adrenal
glands. Brain damage can also occur which may be permanent.
Early symptoms of brain effects are headaches,
lightheadedness, nausea and a feeling of drunkenness. More
serious effects include changes in vision, speech, poor muscle
coordination, shakes, seizures, fits, coma and death.
* Exposure may also increase risk of serious, even life
threatening heart rhythm changes.
Chronic Health Effects
The following chronic (long term) health effects can occur at some
time after exposure to 1,2-Dichloropropane and can last for months
or years:
Cancer Hazard
* There is limited evidence that 1,2-Dichloropropane causes
cancer in animals. It may cause cancer of the liver.
* Many scientists believe there is no safe level of exposure to
a carcinogen. Such substances may also have the potential for
causing reproductive damage in humans.
Reproductive Hazard
* According to the information presently available to the New
Jersey Department of Health, 1,2-Dichloropropane has not been
tested for its ability to adversely affect reproduction.
Other Long Term Effects
* Repeated exposure can damage the liver, kidneys and brai.
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